A History and Atlas of the Human CD4+ T Helper Cell

CD4+ T cells have orchestrated and regulated immunity since the introduction of jawed vertebrates, yet our understanding cell evolution, development, cellular physiology has only begun to be unearthed in past few decades. Discoveries genetic diseases that ablate this population provided insight into their critical functions while transcriptomics, proteomics, high-resolution microscopy recently revealed new insights anatomy physiology. This article compiles historical, microscopic, multi-omics data can used as a reference atlas index dissect within these influential further understand pathologies like HIV infection inflict human cells.